The pace of discovery is going unbelievably fast"
- James Watson
As a cancer genomics researcher at BC Cancer's Genome Sciences Centre (GSC) in Vancouver, Canada, I use and write software to analyze and interpret DNA sequence data from cancer patients
Much has changed in technology and goals since I started my career in genomics in 2000. From Sanger sequencing of SARS, frogs, mice and human genomes or segments of, to 'Next-generation' Illumina sequencing of human cancer.
Over the last 20 years, at the GSC, I have coordinated teams of up to 10 staff in bioinformatics with database development, analysis pipelines, software development, research studies (including two I played a large role in that led to important discoveries), and QA (quality control) of our data and pipelines.
I’m first author on 2 publications in scientific journals and co-author on 56 other refereed articles including 5 on brain cancer listed below.
Currently on leave studying the use of AI (Artificial Intelligence) in cancer research and treatment. This can allow for less invasive and earlier detection of cancer.
Much has changed in technology and goals since I started my career in genomics in 2000. From Sanger sequencing of SARS, frogs, mice and human genomes or segments of, to 'Next-generation' Illumina sequencing of human cancer.
Over the last 20 years, at the GSC, I have coordinated teams of up to 10 staff in bioinformatics with database development, analysis pipelines, software development, research studies (including two I played a large role in that led to important discoveries), and QA (quality control) of our data and pipelines.
I’m first author on 2 publications in scientific journals and co-author on 56 other refereed articles including 5 on brain cancer listed below.
Currently on leave studying the use of AI (Artificial Intelligence) in cancer research and treatment. This can allow for less invasive and earlier detection of cancer.
Research highlights and projects of interest
First author papers or those in which I had a larger role
- My first primary author publication in 2002
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC117194/ - I stayed up to 4am on my own to complete the full genome of the SARS coronovirus in record time in April 2003
http://www.sciencemag.org/content/300/5624/1399.long
See "Cracking the SARS genome" under Media - Linux journal article of the SARS sequencing
http://www.linuxjournal.com/article/6977 - Example of how whole genome sequencing used to determine cancer treatment
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945784/ - A piece of software I wrote in 2014, JAGuaR, to help facilitate RNA-sequencing analysis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111418/
http://www.bcgsc.ca/platform/bioinfo/software/jaguar
In addition to my research work, I have been involved in patient care projects in various of capacities - What matters most to patients about primary healthcare: mixed-methods patient priority setting exercises within the PREFeR (PRioritiEs For Research) project
https://www.ncbi.nlm.nih.gov/pubmed/31292175
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Brain Cancer Research
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