...from Butterfield's first 'build', it's clear they're on track: one section is almost 6,000 base pairs long and another is 7,000 pair long. For the next five hours, they keep reloading. At 2:30 am, Butterfield hits the 'Eureka' moment. Build 28 comes back in one piece, right down to and including the tell-tale polytale - a long string of 'A's that always marks the end of a piece of messenger RNA.
For the wet-lab crew, euphoria gives over to exhaustion. They file out to get some sleep. Butterfield keeps working--analyzing, verifying, comparing the completed sequence to others on file. When Stott comes back at 4 am, he startles Butterfield so badly, he is at risk of being impaled on the pen that Butterfield reflexively flings across the room."
- BC Business Sept. 2003
Thanks to technology and a spirit of global cooperation, the first genome of the virus that causes SARS was mapped by Canadian researchers in less than a week; soon after it was identified as a coronavirus.”
- Newsweek Magazine Apr. 2003
Cracking the SARS Coronavirus Genome - April 2003
The Genome Sequence of the SARS-Associated Coronavirus
Science 30 May 2003
Complete SARS sequence and details
https://www.ncbi.nlm.nih.gov/nuccore/30271926
BC Team unravels SARS
The Province 2003
The Mystery of SARS
Newsweek
Mission Impossible
BC Business 2003
SARS story in (I think only time my photo is in a Chinese magazine)!
Ming Pao Saturday Magazine 2003
Linux journal article of the SARS sequencing
http://www.linuxjournal.com/article/6977
| A Puzzle to Solve |
I'm at my computer, followed by Anca, Obi and Steve Jones, Bioinformatics Leader at BC Genome Sciences Centre
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Saturday night, April 12, 2003, confirming we had the complete sequence
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Our Saturday morning snacks
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